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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSK3A
All Species:
23.03
Human Site:
Y180
Identified Species:
36.19
UniProt:
P49840
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49840
NP_063937.2
483
50981
Y180
V
R
L
R
Y
F
F
Y
S
S
G
E
K
K
D
Chimpanzee
Pan troglodytes
XP_530044
483
51007
Y180
V
R
L
R
Y
F
F
Y
S
S
G
E
K
K
D
Rhesus Macaque
Macaca mulatta
XP_001104964
483
50993
Y180
V
R
L
R
Y
F
F
Y
S
S
G
E
K
K
D
Dog
Lupus familis
XP_852706
441
48143
T146
V
L
E
Y
V
P
E
T
V
Y
R
V
A
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q2NL51
490
51642
Y180
V
R
L
R
Y
F
F
Y
S
S
G
E
K
K
D
Rat
Rattus norvegicus
P18265
483
51008
Y180
V
R
L
R
Y
F
F
Y
S
S
G
E
K
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416557
433
48108
V139
L
D
Y
V
P
E
T
V
Y
R
V
A
R
H
Y
Frog
Xenopus laevis
NP_001083752
420
46885
D124
Y
S
S
G
E
K
K
D
E
V
Y
L
N
L
V
Zebra Danio
Brachydanio rerio
NP_001038386
462
50821
H160
Q
I
M
R
K
L
D
H
C
N
I
V
R
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18431
1067
114422
Y668
V
K
L
L
Y
F
F
Y
S
S
G
E
K
R
D
Honey Bee
Apis mellifera
XP_392504
434
48445
V140
D
E
V
Y
L
N
L
V
L
E
Y
I
P
E
T
Nematode Worm
Caenorhab. elegans
Q9U2Q9
362
40864
L68
M
V
A
I
K
K
V
L
Q
D
K
R
F
K
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZD5
410
46056
R114
Q
D
K
R
Y
K
N
R
E
L
Q
T
M
R
L
Baker's Yeast
Sacchar. cerevisiae
P38615
370
42986
F76
K
V
L
Q
D
K
R
F
K
N
R
E
L
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.7
85.5
N.A.
93.8
97
N.A.
N.A.
67.9
67.4
71.8
N.A.
33.4
64.1
55.2
N.A.
Protein Similarity:
100
99.7
99.7
86.3
N.A.
95.5
97.7
N.A.
N.A.
74.9
74.5
77.6
N.A.
38
75.1
63.7
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
0
0
6.6
N.A.
80
0
6.6
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
13.3
0
33.3
N.A.
93.3
13.3
20
N.A.
Percent
Protein Identity:
N.A.
24.4
N.A.
52.8
40.7
N.A.
Protein Similarity:
N.A.
38.1
N.A.
63.7
55.4
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
0
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
0
0
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
14
0
0
7
0
7
7
0
7
0
0
0
0
40
% D
% Glu:
0
7
7
0
7
7
7
0
14
7
0
47
0
14
0
% E
% Phe:
0
0
0
0
0
40
40
7
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
40
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
7
% H
% Ile:
0
7
0
7
0
0
0
0
0
0
7
7
0
0
7
% I
% Lys:
7
7
7
0
14
27
7
0
7
0
7
0
40
40
0
% K
% Leu:
7
7
47
7
7
7
7
7
7
7
0
7
7
14
7
% L
% Met:
7
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
7
7
0
0
14
0
0
7
0
7
% N
% Pro:
0
0
0
0
7
7
0
0
0
0
0
0
7
0
0
% P
% Gln:
14
0
0
7
0
0
0
0
7
0
7
0
0
0
0
% Q
% Arg:
0
34
0
47
0
0
7
7
0
7
14
7
14
20
7
% R
% Ser:
0
7
7
0
0
0
0
0
40
40
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
7
0
0
0
7
0
0
7
% T
% Val:
47
14
7
7
7
0
7
14
7
7
7
14
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
14
47
0
0
40
7
7
14
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _